Whatfinger News · Health Michael Anthony, Health Writer October 2, 2026
X has a picture of an 80-year-old woman who had barely spoken in years, then ate five grams of mushrooms and started talking again. The posts say she got her life back. The journal is colder, and more useful. A case report in Frontiers in Neuroscience (May 28, 2026) describes an octogenarian with a decade of Alzheimer’s, five of those years in marked decline, who was given 5 grams of an Enigma-strain Psilocybe cubensis. About 19 hours later she was holding a conversation. Over the following days and weeks she regained bladder control she had lost for five years, dressed herself, and walked with less help.
The authors’ own line: residual function became briefly reachable. They do not call it a cure. The gains faded. One woman is not a phase 3 trial. She is also not a group-chat invention. That case is the jump-off for an article I have been writing for weeks. The harder file, what I found out, is the veterans. When you understand what the government, backed by Big Pharma has done in not allowing certain substances to be used, you will be infuriated. As usual, Big Pharma gets their way as they always have. They would prefer to keep a veteran on expensive drugs that put a band-aid on the health issues, for decades. They bilk taxpayers of billions while our people suffer. Well, it’s time to go around the government and try what works to such a large percentage, that it blows away the expensive pills from any Big Pharma company. Documented. Continued under this fast clip
This is insane…
An advanced Alzheimer’s patient just REGAINED her memory, speech, mobility, AND bladder control after a SINGLE dose of psilocybin.
There are NO Alzheimer’s drugs capable of doing anything CLOSE to this. pic.twitter.com/m8qzMrNsFk
— Nicolas Hulscher, MPH (@NicHulscher) October 1, 2026
Nine of twelve
On July 30, 2026, Ohio State published the first U.S. clinical trial of psilocybin-assisted therapy in veterans with severe PTSD who had already failed the usual stack. Twelve people. All had a clinician score of at least 35 on the CAPS-5, which is the severe range. All had already done months on an SSRI or SNRI and at least six months of psychotherapy. Mean starting score: 39.7.
Two doses, with preparation before and integration after. One month after the second dose the mean score was 12.2. That is a 27.5-point drop, Cohen’s d of 2.30, which in psychiatry is a cannon, not a nudge. Nine of the twelve no longer met criteria for PTSD. Ten had a clinically meaningful improvement. No serious adverse events. The common complaint was a headache. Suicidal thinking did not rise.
Prep itself moved the needle, from 39.7 to 33.3, before anyone swallowed a thing. The drug moved it the rest of the way. A read of the same paper put the effect at about 1.8 times psychotherapy-alone studies and close to four times typical PTSD drug trials. Small, open-label, no placebo arm. Still the cleanest American veteran signal on the board.
Clinician PTSD scores in the Ohio State pilot. Severe starts at 35. Remission is 20 or under.

Compass Pathways has a parallel file. In an open-label phase 2 of COMP360, a synthetic psilocybin, 22 adults with severe PTSD got one 25 mg dose plus psychological support. CAPS-5 fell 9.9 points by week 4 and 29.5 points by week 12. Response, defined as a 15-point drop, was 81.8% at week 4 and 77.3% at week 12. Remission, a score of 20 or less, was 63.6% at week 4 and 54.5% at week 12. James Rucker, the principal investigator, noted the obvious: no new medicine has been approved for PTSD in more than 20 years. The FDA has since accepted Compass’s investigational application to run a larger PTSD trial.
One dose, then the week-12 numbers. Open-label, 22 adults, mean starting CAPS-5 of 47.5.

Depression is further along. A 2021 Johns Hopkins randomized trial in major depression reported a 71% clinical response and 54% remission at week 4 in a 24-person cohort. Compass’s phase 3 program in treatment-resistant depression has met its primary endpoint, with a rolling new-drug application aimed at a 2027 launch if the FDA and the DEA both get out of the way. Breakthrough designation for that depression use dates to 2018. The agency has also handed priority-review vouchers to psychedelic programs, psilocybin among them. Washington can move when it feels like it. They get millions from Big Pharma in donations, so not addressing these facts is more important to these low life politicians, than helping or curing our people.
The grocery mushroom is a different animal
Dave Asprey has been on this longer than the VA. On his cheat sheet he splits the legal fungi the way a cook splits a pantry: cordyceps for endurance, reishi for calm, chaga for immunity, lion’s mane for the brain, turkey tail for the gut. He has said lion’s mane extract is the one thing that reliably lengthens his REM sleep, and that skipping a night shows up on the tracker. That is a biohacker’s sleep log, not a dementia trial. It is still the most plain-English map of the supplement aisle. I use the same product. It is not the average Lion’s Mane. The way it is extracted is the key and I tested Dave Asprey’s assertions using my own Oura Ring. He is 100% correct.
Lion’s mane (Hericium erinaceus) has the human data, and it is modest. In 2009, Koichiro Mori randomized 30 Japanese adults, ages 50 to 80, with mild cognitive impairment. Three grams a day of dried fruiting body for 16 weeks. Scores on the revised Hasegawa scale rose at weeks 8, 12, and 16 versus placebo. Four weeks after they stopped, the scores fell. The mushroom worked while they took it. It did not renovate the house. They did not use the variety that Dave Asprey or I use. Here it is, by the way. Just click this baby below or click here. It takes you to Amazon. It is a bit pricey, but you can test yourself using your own wearable like the Oura ring. It worked for me after just one night. Others take a couple. Who wants to sleep better? Practically no one as far as I know. Also, everyone on the Whatfinger News crew now takes this after I did the research and testing myself. Even Sgt Pat, and he hates most supplements.
“As an Amazon Associate I earn from qualifying purchases.”
In 2020, a Taiwanese pilot gave erinacine-A-enriched lion’s mane mycelia to people with mild Alzheimer’s for 49 weeks, the longest run in this literature. The treated group held or improved on MMSE and daily-living scores. Placebo declined, and placebo was the group that lost BDNF and gained amyloid-beta 1–40. The Alzheimer’s Drug Discovery Foundation’s rating is the adult one: a handful of small trials, mixed cognitive results, not enough to call it a treatment. Buy the fruiting body or a real dual extract if you buy anything. A lot of capsules are grain the mycelium grew on, sold as if it were the mushroom.
Turkey tail is the one the cancer wards already use, just not here. Japan’s PSK extract (Krestin), from Trametes versicolor, has been an approved adjunct since the 1970s. The National Cancer Institute’s summary covers gastric, colorectal, and lung trials in which PSK alongside standard care was tied to better immune recovery and, in some series, longer survival. That is a purified drug in a national formulary. It is not a $28 bag from the vitamin shop, and it is not a reason to skip chemotherapy. Here’s the product I use this a few days a month at most, as I do not have cancer, but use it more as a preventative. – At Amazon this is the one. The company that sells it is pretty good for all of their supplements
Four lanes, four grades of proof. Grocery capsules are not the clinic dose.

The bill
PTSD cost the country an estimated $232.2 billion in excess burden in 2018, about $19,630 per person with the diagnosis and $25,684 in the military and veteran population. Disability payments and direct care carry the veteran share. Civilians carry most of the total, because there are more of them. You’ve all seen how many Democrat scams have been exposed just since Elon Musk and his DOGE group went to work. This Big Pharma scam alone is worth billions to their companies, which means the politicians want PTSD to say, causing untold suffering by our people while they get rich off our tax dollars. Seriously, one day if there were ever a real revolution in America, I do not think any Big Pharma execs or Democrats in office (RINOS as well) will survive it.
Dementia is the other ledger. The Alzheimer’s Association projects health and long-term care for people with Alzheimer’s and other dementias at $409 billion in 2026, before you count unpaid family labor. In 2025 that unpaid care ran past 19 billion hours, valued above $446 billion. Lifetime cost per person was estimated at $405,262 in 2024 dollars, and families eat about 70% of it in time and cash. Medicaid spending on a person with dementia runs about 22 times the spend on an older adult without it.
2018 PTSD excess costs next to the 2026 dementia projection. Different years, same argument.

Nobody honest will promise that a mushroom protocol zeroes that out. A veteran trial that puts three-quarters of treatment-resistant cases into remission at one month, if it survives a placebo-controlled redo, is a disability-roll problem for the VA and a life problem for the people on it. A grocery mushroom that holds a mild cognitive score for as long as you take it is a cheaper bet than another year of decline, and it is legal this afternoon.
Seriously…
One shelf is culinary and supplemental: lion’s mane, turkey tail, reishi, cordyceps. Legal. Dose ranges come from the trials, not from a podcast. Lion’s mane in the Mori trial was 3 grams a day of fruiting-body powder, and the benefit left when the powder did. Turkey tail’s real clinical product is PSK, not a random capsule. Chaga has antioxidant chatter and also case reports of liver trouble and oxalate kidney stones. Skip it if your liver or your kidneys already have a file. The Lion’s Mane I linked above is far superior, with results you can see right on your Oura Ring overnight.
The other shelf is psilocybin. Still Schedule I federally. The trials that moved PTSD and depression scores used screened patients, a measured dose, and a clinician in the room. The Alzheimer’s case included profuse sweating, a suspected fever, and a 19-hour sleep. Leave that to a protocol with consent and a clinician, not a Sunday experiment on a relative who cannot meaningfully agree. Oregon and Colorado have opened state lanes. The FDA is inching Compass toward a depression approval and has cleared a larger PTSD study. Until a label exists, the honest public line is the trial line: promising, small, not a home protocol. You know I cannot say it cures. But you know how that goes. The low lifes in media banned Whatfinger News at the beginning of the Covid BS, for daring to tell you the truth. They, and the government would do far worse if we tell you the truth here, but you can read between the lines.
Asprey’s point, and the point of the Nature brain-scan work he flagged this spring, is that these compounds hit the same large-scale brain networks from different directions. Psychiatry has spent 20 years renewing the same two PTSD pills. Japan has been handing cancer patients a mushroom extract since disco. Twelve veterans in Columbus just posted a remission rate the formulary has not touched.
If the redo trials hold, the savings are not a slogan. They are disability checks, caregiver hours, and a woman who got a few weeks of her own voice back. That is worth a section. It is not worth a miracle headline.
I’ll end this just saying: If I had Alzheimer’s, I would 100% take a dose of Mushrooms. I don’t care if it is illegal or legal anywhere, my health, is my health. Screw the government and Big Pharma. Same for PTSD. I have a few military buddies, and Sgt Pat, one of our editors has many stories about how the VA tortured patients in the past (before Trump) as Democrats detest our military men and women. The prevented medications, and many turned to mushrooms, and overnight, Sgt Pat says 70 or 80% no longer had PTSD. So, basically, do what you need to do for YOUR health, or the loved ones under your care. Big Pharma and the government DO NOT have the best interests of our people in mind, ever.
–— The Whatfinger News Team: Michael Anthony, Health Writer, with Beth, and Grok on edits and graphics
References
- Transient multidomain functional improvement in advanced Alzheimer’s after high-dose psilocybin mushrooms — Lago et al., Frontiers in Neuroscience, May 28, 2026
- Woman with Alzheimer’s starts conversing again after taking psilocybin — New Scientist, June 22, 2026
- For veterans with severe PTSD, psilocybin-assisted therapy may help — Ohio State / EurekAlert, July 30, 2026
- Safety and preliminary outcomes of psilocybin-assisted therapy for veterans with treatment-resistant PTSD — Armstrong et al., Communications Medicine, 2026
- Veterans with severe PTSD saw major improvement after psilocybin treatment — Earth.com, August 22, 2026
- Phase 2 study of COMP360 psilocybin finds improved PTSD symptoms — Psychiatric Times
- FDA accepts investigational new drug application for COMP360 for PTSD — Psychiatric Times
- Effects of psilocybin-assisted therapy on major depressive disorder — Davis et al., JAMA Psychiatry, 2021
- New 6-month data from second phase 3 trial of COMP360 for treatment-resistant depression — Psychiatric Times
- FDA grants priority vouchers to psychedelic medications — Managed Healthcare Executive
- Dave Asprey on lion’s mane and REM sleep — Lifecykel / Bulletproof Radio
- Improving effects of Yamabushitake on mild cognitive impairment — Mori et al., Phytotherapy Research, 2009
- Prevention of early Alzheimer’s by erinacine A-enriched Hericium erinaceus — Li et al., Frontiers in Aging Neuroscience, 2020
- Lion’s mane cognitive-vitality rating — Alzheimer’s Drug Discovery Foundation
- Medicinal mushrooms PDQ, turkey tail and PSK — National Cancer Institute
- Economic burden of PTSD — VA HSR&D brief on Davis et al., Journal of Clinical Psychiatry, 2022
- By the numbers: the cost of PTSD — American Psychological Association
- 2026 Alzheimer’s Disease Facts and Figures — Alzheimer’s Association
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